Biomedical Engineering
   
http://portal.bm.technion.ac.il/SiteCollectionImages/shulamit.jpgShulamit Levenberg , Associate Professor
Affiliation: Faculty
Link to Lab Web Page:
 

Office: Silver 169
Phone: +972(4)8294810
E-mail Address: shulamit@bm.technion.ac.il
Office: Silver 169
Phone: +972(4)8294810E-mail Address: shulamit@bm.technion.ac.il

Education:
1999: Ph.D., Direct Ph.D. program, Molecular Cell Biology Department,  Weizmann Institute of Science, Rehovot, Israel. Supervisor: Prof. Benjamin Geiger.
Thesis: The Structure and Function of Adhesion Signaling Complexes
1992: B.Sc., Magna Cum Laude, Biology, Faculty of Life Sciences, Hebrew University,Jerusalem, Israel

Academic appointments:
May 2009- present:  Associate Professor, Biomedical Engineering Department, Technion, Israel Institute of Technology
Oct. 2004-  April 2009:  Senior Lecturer, Biomedical Engineering Department, Technion, Israel Institute of Technology
Summer 2006: Visiting Scientist, Prof. Robert Langer Lab, Chemical Engineering Department, MIT
Sept. 2002- July 2004:  Research Associate, Prof. Robert Langer Lab, Chemical Engineering Department, MIT.
Sept. 2001- Aug 2002:  Post Doctorate Associate, Prof. Robert Langer Lab, Chemical Engineering  Department, MIT.
Sept. 1999- Aug 2001:  Post Doctorate fellow, EMBO Fellowship, Prof. Robert Langer Lab, Chemical & Biomedical Engineering Department, MIT.

Short Bio:
Prof. Levenberg conducts interdisciplinary research on stem cells and tissue engineering. She did her PhD at the Weizmann institute on cell adhesion, and her post doctorate research on tissue engineering with Prof. Robert Langer at MIT. Her research showed that it is possible to create complex tissues including blood vessels in a laboratory and that these engineered tissue-constructs can integrate with the host when implanted. She is also developing micro bioreactors and nanoliter droplet devices for stem cell growth and manipulations. Levenberg received the Krill Prize for excellence in scientific research by the Wolf Foundation, and was named by Scientific American as a “Research Leader” in Tissue Engineering. Prof. Levenberg is currently the elected president of the Israel Stem Cell Society and serves as a member of the Israel National Bioethics Council..

Research interests:
Vascularization of engineered tissues. Stem cell differntiation on 3D scaffolds.Controling stem cell microenvironments

Publications:
  1. Levenberg, S., Rouwkema, J., Macdonald, M., Gerfein, E., Kohane, D., Darland D., Marini, R., van Blitterswijk, C.A., Mulligan, R., D’Amore, P. and Langer, R. Engineering Vascularized Skeletal Muscle Tissue.  Nature Biotechnology. 23:879-884. (2005)  Cited as a Landmark paper is Nature Biotechnology News and Views.
  2. Caspi O. and Lesman A., Basevitch Y., Gepstein A., Arbel G., Habib M., Gepstein L., and Levenberg S. Tissue Engineering of Vascularized Cardiac Muscle from Human Embryonic Stem Cells. Circulation Research. 100(2):263-72. (2007)
  3. Korin N., Bransky A., Dinnar U. and Levenberg  S. A Parametric Study of Human  Fibroblasts Culture in a Microchannel Bioreactor. Lab on a Chip, 7, 611 – 617. (2007)
  4. Levenberg, S., Zoldan J., Bashevits Y. and Langer, R. Endothelial potential of Human Embryonic Stem Cells. Blood. 110(3):806-14 (2007)
  5. Levy-Mishali M., Zoldan J and Levenberg S. Effect of Scaffold Stiffness on Myoblast Differentiation. Tissue Engineering. Part A. Apr;15(4):935-44. (2009) 
  6. Bransky A., Korin N., Khoury M. and Levenberg S. A Microfluidic Droplet Generator Based on a Piezoelectric Actuator. Lab on a chip. Feb 21;9(4):516-20. (2009).
  7. Lesman A., Habib M., Gepstein A., Arbel G., Levenberg S. and Gepstein L.    Transplantation of Tissue-Engineered Human Vascularized Cardiac Muscle. Tissue Engineering Part A.  16(1):115-25. (2009)
  8. Lesman A., Blinder Y. and Levenberg S. Modeling of flow-induced shear-stress applied on 3D cellular scaffolds for vascular tissue-engineering applications. Biotechnology and Bioengineering. 105(3):645-54. (2009)
  9. Levenberg S., Ferreira L., Chen-Konack L., Kraehenbuehl T, and Langer R. Isolation, differentiation, and characterization of vascular cells derived from human embryonic stem cells. Nature Protocols. 5(6):1115-26. (2010)
  10. Lesman A., Gepstein L. And Levenberg S.Vascularization shaping the heart. Ann N Y Acad Sci.1188:46-51 (2010)
  11. Shemesh J., Bransky A., Khoury M. and Levenberg S. Advanced microfluidic droplet    manipulation based on piezoelectric actuation. Biomedical Microdevices (2010) In print.

For full list of publication clik here


Honors and Awards:
2009:TEVA Research Award
2009:"The Excellences of Israel" prize, Italy
2008:France-Israel Foundation Prize for scientific excellence in stem cell research
2007:"Yediot Acharonot" newspaper list of 50 people of the year
2007:The Henry Taub Prize for Academic Excellence
2006:2006 Scientific American 50 Award- Research Leader in Tissue Engineering
2006:Krill Prize of the Wolf Foundation for excellence in scientific research
2006-2007: Marie Curie International Reintegration Grant Leader in Engineering
2004:Landau Fellow, Leaders in Science and Technology program
2004:ASAIO (American Society for Artificial Internal Organs) Willem J. Kolff Young Investigators Award
1999-2001: EMBO (European Molecular Biology Organization) Long-Term Post-doctoral fellowship
1999:Fulbright Israeli Post-doctoral award
1990-1992: Dean’s List, Faculty of Life Sciences, Hebrew University, Israel
1990:Excellence award by the Faculty of Life Sciences, Hebrew University