The Coronary Circulation
The function of the coronary circulation is to convey blood to the capillary network and to nourish the myocardium. Ischemic heart diseases, which impair the coronary flow, are the most common cause of morbidity and mortality in the western world. Coronary flow is of pivotal importance in determining biological responses leading to initiation of common pathologies such as atherosclerosis and hypertensive remodeling.
The excessive difficulties in measuring flow in-vivo, leaves computerized simulation as the only viable methodological alternative to address questions and dilemmas of high clinical and research importance